Of the more than 8,400 participants followed for over 23 years in the PREVEND study, around 10% developed heart failure. Rising NT-proBNP levels were found to be strongly associated with HFrEF (heart failure with reduced ejection fraction), a condition where the pumping power of the heart is significantly diminished. This association was most pronounced in women.
Dr. Navin Suthahar (MD, MSc, PhD), Assistant Professor at the Department of Cardiology in Erasmus MC, led the study. Suthahar: “Our understanding of these biomarkers is continuously evolving. Regularly measuring NT-proBNP can help identify women at increased risk for this type of heart failure sooner. Our research opens the door to early prevention and targeted treatments.
The publication may be found here.