What causes obesity, how does it lead to illness, and how does one tailor treatment to a patient’s personal situation? These are questions that the Obesity Center CGG at Erasmus MC is looking to answer.
Organoids made from liver tissue of patients with chronic hepatitis B already show the first molecular signs of liver cancer. This has been demonstrated by scientists at Erasmus MC and the the Hubrecht Organoid Technology (HUB).
Only 40 patients worldwide are known to have Barakat-Perenthaler syndrome, a severe untreatable form of epilepsy. Four years after discovering the disease, its Rotterdam namesakes are now on the trail of a treatment.
Researchers at Erasmus MC are able to keep slices of human heart tissue alive for several months in the laboratory. This enables them to test patient-specific treatments for heart failure and arrhythmia and possibly predict early rejection of donor hearts in the future.
At what age a woman reaches the menopause is partially decided by genetics. Especially genes for maintenance and repair of DNA are of importance. This has been shown by research involving scientists from Rotterdam.
Children and medications are often not a good combination. The pills are too big, taste awful or the dosage is incorrect. Erasmus MC and TNO are starting research into a possible solution: personalized pills from a 3D printer.
In a joint research project with Delft University of Technology and Leiden University Medical Center, internist-oncologist Stefan Sleijfer is looking for a drug that can prevent cancer from spreading. Remarkable: the researchers are searching in a library of substances that are already used in daily practice.